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Bovine

VetMAX™ Reagents Deliver Specific, Reproducible Amplification of Target Nucleic Acid Sequences.

Economic Significance of Tritrichomonas foetus (T. foetus)
Tritrichomonas foetus is a parasite that causes a venereal disease of cattle characterized primarily by early fetal death and infertility, which results in extended calving intervals. Although T. foetus can survive semen cryopreservation, it can’t survive drying or high temperatures. The disease is a threat for cattle-producers in Texas, because breeding bulls entering Texas must be no more than 24 months of age or younger and certified as virgins--or test negative for cattle trichomoniasis within 30 days prior to entry.  Many other major cattle-producing states have similar programs, which either require (or highly recommend) that bulls be tested for T. foetus before entry into the state.

Benefits of PCR:  Real-time PCR is the most sensitive method for amplifying Tritrichomonas foetus DNA.  Many states will accept one negative RT-PCR test as certification.

Economic Significance of Bovine Herpesvirus 1 / Infectious Bovine Rhinotracheitis (IBR/BHV-1)
Bovine herpesvirus 1 (BHV-1) infections are widespread in cattle - IBR respiratory form is most common among feedlot cattle. The viral infection alone is not life threatening, but predisposes the animal to secondary bacterial pneumonia, which may result in death. Cattle with latent BHV-1 infections generally show no clinical signs when the virus is reactivated, but serve as a source of infection for other susceptible animals.

Benefits of PCR: Diverse sample matrices can be tested, such as semen, smegma, and nasal and genital swabs. DNA isolation and qRT-PCR can easily be automated for high-throughput processing.

Economic Significance of Bluetongue Virus (BTV)
Bluetongue is a viral disease spread by certain types of biting midges. It affects all ruminants, including sheep, cattle, deer, goats, and camelids (camels, llamas, alpacas, guanaco, and vicuna). It does not affect horses or pigs, but the disease can produce significant losses per herd due to the spread of illness, resulting in reduced productivity and death.

Economic Significance of Bovine Respiratory Syncytial Virus (BRSV)
Bovine respiratory syncytial virus (BRSV) is an RNA pneumo-virus in the paramyxovirus family. BRSV is an important virus in the bovine respiratory disease complex because of its frequency of occurrence, predilection for the lower respiratory tract, and ability to predispose the respiratory tract to secondary bacterial infection leading to high morbidity and mortality in calves and feedlot cattle.

Benefits of PCR: PCR is the most sensitive method for amplifying virus RNA.  Diverse sample matrices can be tested, such as semen, smegma, and nasal and genital swabs. DNA isolation and qRT-PCR can easily be automated for high-throughput processing.

Economic Significance of Mycobacterium avium subsp. paratuberculosis (MAP) Johne's Disease
The bacterial disease known as Johne’s disease results in significant loss to the livestock industry. Johne’s disease occurs in many countries and is one of the most economically important diseases in cattle. The effects of this contagious disease include reduced milk production, fetal loss, and early death.

Benefits of PCR: Real-time PCR for MAP delivers the best balance of sensitivity and specificity.