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POROS® Analytical Chromatography Columns

High Performance Resin for Analytical and Lab-Scale Separations

POROS Analytical Columns, with 10 and 20 micron particle size resins, deliver excellent resolution at high speed for both analytical and lab-scale preparative applications.

POROS Protein A Analytical Columns are the industry standard for monitoring monoclonal antibody titer and yield from cell culture supernatant.


  • Affinity

    Affinity Resin

    • POROS® A 20 µm Columns, PEEK™
      Prepacked Protein A Affinity Column is based on an immobilized recombinant Protein A functional group designed for high throughput purification of antibodies.
    • POROS® G 20 µm Columns, PEEK™
      Prepacked Protein G Affinity Column is based on an immobilized recombinant Protein G functional group designed for high throughput purification of antibodies.

    Activated Affinity Resin

    • POROS® AL 20 µm Columns, PEEK™
      Prepacked Immobilized Aldehyde Affinity Column is based on an aldehyde functional group designed for the immobilization of proteins through free amine groups.
    • POROS® EP 20 µm Columns, PEEK™
      Prepacked Immobilized Epoxide Affinity Column is based on an epoxide functional group designed for the immobilization of proteins through free amine groups.
    • POROS® OH 20 µm Columns, PEEK™
      Prepacked Immobilized Hydroxyl Affinity Column is based on an hydroxylated functional group designed for the immobilization of proteins through activation with tresyl-chloride, divinyl-sulphone or cyanogen bromide.
  • Ion Exchange

    • POROS® HQ 20 µm Columns, PEEK™
      Prepacked Strong Anion Exchange Column is based on a quarternized polyethyleneimine functional group yielding a high capacity, Perfusion Chromatography® media designed for the separation and purification of biomolecules.
    • POROS® PI 20 µm Columns, PEEK™
      Prepacked Weak Anion Exchange Column is based on a polyethyleneimine functional group yielding a high capacity, Perfusion Chromatography® media designed for the separation and purification of biomolecules.
    • POROS® HS 20 µm Columns, PEEK™
      Prepacked Strong Cation Exchange Column is a high capacity, strong cation exchange Perfusion Chromatography® media suitable for the separation and purification of biomolecules.
    • POROS® S 20 µm Columns, PEEK™
      Prepacked Strong Cation Exchange Column is a strong cation exchange Perfusion Chromatography® media, suitable for the separation and purification of biomolecules.
  • Metal Chelate


    POROS®  MC 20 µm Columns, PEEK™
    Prepacked Immobilized Metal Affinity Column is based on a Imido-diacetate functional group designed for the purifiction of proteins that form co-ordination complexes via metal sites and specific amino acids, such as histidine tagged fusion proteins.
  • Hydrophobic Interaction


    POROS® HP 20 µm Columns, PEEK™
    Prepacked Hydrophobic Interaction Chromatography Column is a high density phenyl, Perfusion Chromatography® media suitable for the separation and purification of proteins.
  • Reversed-Phase

    • POROS® R2 20 µm Columns, PEEK™
      Prepacked Reversed-Phase Column is a 2000 angstrom pore size Poly (Styrene-Divinylbenzene) particle, suitable for the reversed-phase separation of biomolecules.
    • POROS® R1 20 µm Columns, PEEK™
      Prepacked Reversed-Phase Column is a 4000 angstrom pore size Poly (Styrene-Divinylbenzene) particle, suitable for the reversed-phase separation of biomolecules.
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