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POROS® Bulk Chromatography Resin

High Performance Resin for Process-Scale Separations

When you need high performance and high throughput on a large scale, POROS® Bulk Chromatography Resins are the industry standard for process-scale bioseparations.

Utilized in multiple FDA regulated processes, these breakthrough resins combine optimal particle size and pore structure with a rigid backbone and proprietary chemistries. POROS® 50 µm resins demonstrate exceptionally high dynamic binding capacity, capture efficiency, and resolution over a range of flow rates.

POROS® products are manufactured in a state-of-the-art chromatography resin manufacturing facility and tested using the highest quality standards to support use in regulated biotherapeutic markets.

POROS XS Sample  

The new POROS® XS Cation Exchange Resin delivers:

  • Dynamic binding capacity for proteins, greater than 100 mg/mL at 5% breakthrough

  • High resolution using optimized 50 μm particle size for improved impurity clearance

  • Robust salt tolerance that maintains dynamic binding capacity to 150 mM NaCl (15 mS/cm)
Learn More about POROS® XS >

  • POROS® XS 50 µm Bulk Resin
    A cation exchange resin that delivers the combination of high capacity, high resolution, and high salt tolerance can lead to increased process efficiency and help enable a faster time to market for the product.
  • POROS® HQ 50 µm Bulk Resin
    Strong Anion Echange Resin available for low pressure applications, including large scale downstream bioprocessing. POROS® HQ is based on a quaternized polyethyleneimine functional group yielding a high capacity, Perfusion Chromatography® media designed for the separation and purification of biomolecules.
  • POROS® PI 50 µm Bulk Resin
    Weak Anion Echange Resin for low pressure applications, including large scale downstream bioprocessing. POROS® PI is based on a polyethyleneimine functional group yielding a high capacity, Perfusion Chromatography® media designed for the separation and purification of biomolecules.