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Methylation Analysis

DNA methylation is involved in the regulation of many cellular processes, including X chromosome inactivation, chromosome stability, chromatin structure, embryonic development and transcription. Bisulfite sequencing is the gold standard in validation of methylation experiments as only sequencing provides direct detection of methylation events as well as information across the entire region. Applied Biosystems provides an integrated solution for methylation analysis with optimized protocols for each step. 

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