Microsatellite STR Analysis
Figure 1: 18 Microsatellite Loci
Microsatellite genotyping is the genotyping of tandem repeats such as Short Tandem Repeats (STRs) or Variable Nucleotide Tandem Repeats (VNTRs). STRs and VNTRs are polymorphic DNA loci present throughout the genome. Microsatellite genotyping is a widely accepted tool for a variety of applications such as linkage mapping studies, association studies, and identification of organisms.
Applied Biosystems' five-dye chemistry increases the number of microsatellite markers that can be run in a single capillary, for improved throughput. Figure 1 is an example of 18 microsatellite loci co-electrophoresed in a single capillary.
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