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Resequencing Heterozygote Detection

Accurate heterozygous indel mutation detection on an Applied Biosystems Genetic Analyzer.

Heterozygote detection identifies heterozygous base positions or small insertions/deletions in genomic DNA. This technique is of great utility in locating mutations or polymorphisms in diploid organisms. The technique is widely used to identify carriers of a given trait. Subsequently, mutation profiling precisely and comprehensively defines the genetic changes responsible for disease development or susceptibility at the molecular level.

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